4-[4-(4-chlorophenyl)- 4-hydroxy-1-piperidyl]- N,N-dimethyl- 2,2-diphenyl-butanamide
Loperamide the active ingredient in almost all anti diarrhoea products such as immodium and gastro stop. It is an opioid with reacts in an agonistic fashion within the myentric plexus within the large intestine. On binding it reacts to reduce the amount of intestinal motility via a protein kinase cascade. Reducing the amount of movement in the intestine allows the faecal material to shed large amounts of water and allows the material to solidify reducing the risk of dehydration. reducing movement can also help to stem nausea, reduce vomiting.
This is possibly one of the most useful drugs in human history allowing people all over the world the ability to go to work, get on aircraft and enjoy a honeymoon, without the embarrassment of diarrhoea.
However once your wife passes out on an aircraft on arrival at Singapore, looking pale, there is only one real option. Hospital and cancel the flight.
Ladies, gentlemen and Homo Escapeons, we did not make it to South Africa, a few less baboons got counted. But we managed to salvage what could have been a disaster into a few amazing days in Singapore, enjoying the food (black pepper crab), the people(my brother in-laws gf is a local and played tour guide), the world class zoos (we even saw baboons) and the amazing specials on; well everything (50 Singapore dollars 1 gig memory card).
We are now back home alive and well, and are now playing the happy couple, setting up house buying furniture, cutlery and a new dinner set with all the gift vouchers we received.
My fathers advice to me on the wedding day was...
"Son on the first night you are asked to do dishes as man and wife, drop two of the most expensive dishes you own and you will never be asked to do them again. Never do anything well you do not wish to do again."
I am sure stace over heard this as the new set is nearly an inch think stone ware, but the black and purple looks awesome.. Dad's advice also concerns me as I am also (biological) an only child... hrmmm.