Tuesday, December 05, 2006

4-[4-(4-chlorophenyl)- 4-hydroxy-1-piperidyl]- N,N-dimethyl- 2,2-diphenyl-butanamide

Loperamide the active ingredient in almost all anti diarrhoea products such as immodium and gastro stop. It is an opioid with reacts in an agonistic fashion within the myentric plexus within the large intestine. On binding it reacts to reduce the amount of intestinal motility via a protein kinase cascade. Reducing the amount of movement in the intestine allows the faecal material to shed large amounts of water and allows the material to solidify reducing the risk of dehydration. reducing movement can also help to stem nausea, reduce vomiting.

This is possibly one of the most useful drugs in human history allowing people all over the world the ability to go to work, get on aircraft and enjoy a honeymoon, without the embarrassment of diarrhoea.

However once your wife passes out on an aircraft on arrival at Singapore, looking pale, there is only one real option. Hospital and cancel the flight.

Ladies, gentlemen and Homo Escapeons, we did not make it to South Africa, a few less baboons got counted. But we managed to salvage what could have been a disaster into a few amazing days in Singapore, enjoying the food (black pepper crab), the people(my brother in-laws gf is a local and played tour guide), the world class zoos (we even saw baboons) and the amazing specials on; well everything (50 Singapore dollars 1 gig memory card).

We are now back home alive and well, and are now playing the happy couple, setting up house buying furniture, cutlery and a new dinner set with all the gift vouchers we received.

My fathers advice to me on the wedding day was...

"Son on the first night you are asked to do dishes as man and wife, drop two of the most expensive dishes you own and you will never be asked to do them again. Never do anything well you do not wish to do again."
I am sure stace over heard this as the new set is nearly an inch think stone ware, but the black and purple looks awesome.. Dad's advice also concerns me as I am also (biological) an only child... hrmmm.


Blogger Homo Escapeons said...

HA! I am sure that he wasn't referring to you know what.
Poor Stace..that must have been scary.
The baboons will be there when you are ready to go back. I am glad to hear that you made the most of it..I am trying so hard to not make any honeymoon jokes here...anyway I also want to tell you how much I enjoy learning about Cindi Loper-amide.
I was ready for an even deeper probe of diarrhea.. on a diatomic level it doesn't even sound gross!

5:55 AM  
Blogger Within Without said...

Welcome back, you two. Congratulations and watch those plates.

I can email some pix of baboons if you like.

12:44 PM  
Blogger lee said...

So your Dad's good with the advice, but maybe not so good at..... It wouldn't have been a real honeymoon without at least one disaster -real life begins :).

7:18 PM  
Blogger Keshi said...

Singapore would have been a terrific getaway. Glad u enjoyed it :)

**Never do anything well you do not wish to do again."

LOL ur dad's cheeky!


8:50 PM  
Blogger Perspective Inc. said...


2:20 PM  
Blogger Aidan said...

HE: deeper probe of diarrhoea, not too much to say... possibly an analogy between skatol (what makes faeces smell) and serotonin both synthesised from tyrosine.. One is produced in the head and one in the bowel. There is a genetic condition where this is reversed producing people with brains in their bum and shit for brains. See also politition...

Thaks for the offer WW, we did get to see some in Singapore but we started feeling flat abou the trip we missed.

Thanks lee, it oficial now i guess... It was good for the relationship, really tesed out the in SICKNESS part of the vows...

Keshi my dad has a wicked sense of humour as i said on your blog... HUge heart but somewhat tragic sense of fashion.

Perspective thanks:)

Ok my wife is kissing the back of my neck that can only mean one thing...

She wants to use the computer:)

9:20 PM  
Blogger Alicia said...

Congrats on the wedding, sorry the honeymoon didn't go as planned. Hell, we've been married almost 7 years (the 10th) and didn't even have a honeymoon!

You know that kissing the back of your neck could mean MORE. lol

4:55 AM  
Blogger Homo Escapeons said...

How are you enjoying the brushfire hazing? Married life treating you alright...I would really appreciate the chemical formula for the shit-for-brains condition...If we could cure that syndrome there might be a Nobel in it for us??!!

7:09 PM  

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